Legg-Calve-Perthes disease
Legg-Calve-Perthes disease
Definition
A hip region disease that is characterized by uni- or bilateral avascular necrosis (AVN) of the femoral head in children. In a small percentage of cases, mutations in the COL2A1 gene were found to be responsible.
Also known as aseptic necrosis of the capital femoral epiphysis, Legg Calvé Perthes Disease, Legg-CALVE-Perthes disease, Legg-Calve-Perthes symptom, Legg-Calve-Perthes syndrome, Legg-Perthes disease, osteochondritis of the capital femoral epiphysis, Osteochondrosis of the capital femoral epiphysis, Perthe's disease, Perthes disease — per MONDO
Also identified as
- DOID 14415 per MONDO
- MESH D007873 per MONDO
- NCIT C34766 per MONDO
- OMIM 150600 per MONDO
- Orphanet 2380 per MONDO
- SCTID 15739006 per MONDO
- UMLS C1442965 per MONDO
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Bone element | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Bone element | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Connective tissue | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Musculoskeletal system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Musculoskeletal system | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |