Medulloblastoma

Medulloblastoma

Definition

A malignant, invasive embryonal neoplasm arising from the cerebellum. It occurs predominantly in children and has the tendency to metastasize via the cerebrospinal fluid pathways. Signs and symptoms include truncal ataxia, disturbed gait, lethargy, headache, and vomiting. There are four histologic variants: classic medulloblastoma, large cell/anaplastic medulloblastoma, desmoplastic/nodular medulloblastoma, and medulloblastoma with extensive nodularity.

Also known as cerebellum embryonal neoplasm, medulloblastoma, medulloblastoma, autosomal recessive, autosomal dominant, somatic mutation, medulloblastoma, desmoplastic, autosomal recessive, autosomal dominant, somatic mutation, medulloblastoma, malignant, medulloblastoma, somatic, medulloblastomas — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Brain Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Brain Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Central nervous system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Central nervous system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Cerebellum Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Cerebellum Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Nervous system Disease Has Associated Anatomic Site NCIT · CC BY 4.0

Drugs indicated

Drug Relation Source
Carmustine may treat MEDRT · Public domain (U.S. Government work)