Osteosarcoma

Definition

A usually aggressive malignant bone-forming mesenchymal neoplasm, predominantly affecting adolescents and young adults. It usually involves bones and less frequently extraosseous sites. It often involves the long bones (particularly distal femur, proximal tibia, and proximal humerus). Pain with or without a palpable mass is the most frequent clinical symptom. It may spread to other anatomic sites, particularly the lungs.

Also known as osteogenic sarcoma, osteoid sarcoma, osteosarcoma, osteosarcoma (disease), osteosarcoma, malignant, sarcoma of osteoid — per MONDO

Also identified as

• DOID 3347 per MONDO
• MESH D012516 per MONDO
• NCIT C9145 per MONDO
• UMLS C0029463 per MONDO

Drugs indicated