Theophylline

ATC Code R03DA04

Theophylline

Definition

A natural alkaloid derivative of xanthine isolated from the plants Camellia sinensis and Coffea arabica. Theophylline appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Physiologically, this agent relaxes bronchial smooth muscle, produces vasodilation (except in cerebral vessels), stimulates the CNS, stimulates cardiac muscle, induces diuresis, and increases gastric acid secretion; it may also suppress inflammation and improve contractility of the diaphragm. (NCI04)

Also known as 1,3-Dimethylxanthine Monohydrate, 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione, 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione Monohydrate, Constant-T, Elixophyllin, LaBID, Respbid, Slo-bid, Slo-Phyllin, Somophyllin-CRT, Somophyllin-T, T-Phyl, Theo-24, Theobid Duracap, Theochron, THEOPHYLLINE, Theophylline Monohydrate, Uniphyl — per NCIT

Also identified as

Indications

Disease Relation Source
Asthma may treat MEDRT · Public domain (U.S. Government work)
Bronchitis may treat MEDRT · Public domain (U.S. Government work)
Pulmonary emphysema may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Lungs may treat a disease of this organ DERIVED · CC BY 4.0
Respiratory system may treat a disease of this organ DERIVED · CC BY 4.0

2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.