Ursodeoxycholic acid

Definition

A synthetically-derived form of ursodiol, a bile acid produced by the liver and secreted and stored in the gallbladder. Also produced by the Chinese black bear liver, ursodiol has been used in the treatment of liver disease for centuries. This agent dissolves or prevents cholesterol gallstones by blocking hepatic cholesterol production and decreasing bile cholesterol. Ursodiol also reduces the absorption of cholesterol from the intestinal tract.

NCIT:C1818 · NCI Thesaurus OBO Edition · CC BY 4.0 mapping unreviewed

Also known as (3alpha,5beta,7beta)-3,7-Dihydroxycholan-24-oic acid, Actigall, Deursil, UDCA, URSO, Ursodeoxycholic Acid, URSODIOL — per NCIT

Also identified as

ATC A05AA per NCIT
NCIT NCIT:C1818 per NCIT

Indications

Disease	Relation	Source
Cholelithiasis	may prevent	MEDRT · Public domain (U.S. Government work)
Cholelithiasis	may treat	MEDRT · Public domain (U.S. Government work)
Primary biliary cholangitis	may treat	MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ	Side effect / interaction	Source
Alimentary part of gastrointestinal system	may treat a disease of this organ	DERIVED · CC BY 4.0
Bile ducts	may treat a disease of this organ	DERIVED · CC BY 4.0
Gallbladder	may treat a disease of this organ	DERIVED · CC BY 4.0
Liver	may treat a disease of this organ	DERIVED · CC BY 4.0

4 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.