Primary biliary cholangitis
ICD-10 Code
K74.3
Category
Autoimmune
Primary biliary cholangitis
Definition
Primary biliary cholangitis (PBC) is a chronic and slowly progressive cholestatic liver disease of autoimmune etiology characterized by injury of the intrahepatic bile ducts that may eventually lead to liver failure.
Also known as chronic non-suppurative destructive cholangitis, chronic nonsuppurative destructive cholangitis, Hanot syndrome, PBC, primary Bilary cirrhosis (PBC), primary biliary cirrhosis — per MONDO
Also identified as
- DOID 12236 per MONDO
- ICD10CM K74.3 per MONDO
- ICD9 571.6 per MONDO
- MESH D008105 per MONDO
- NCIT C27167 per MONDO
- Orphanet 186 per MONDO
- SCTID 31712002 per MONDO
- UMLS C0008312 per MONDO
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Alimentary part of gastrointestinal system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Alimentary part of gastrointestinal system | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Bile ducts | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Bile ducts | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Biliary system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Liver | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Liver | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
Drugs indicated
| Drug | Relation | Source |
|---|---|---|
| Colchicine | may treat | MEDRT · Public domain (U.S. Government work) |
| Elafibranor | may treat | MEDRT · Public domain (U.S. Government work) |
| Penicillamine | may treat | MEDRT · Public domain (U.S. Government work) |
| Seladelpar | may treat | MEDRT · Public domain (U.S. Government work) |
| Ursodeoxycholic acid | may treat | MEDRT · Public domain (U.S. Government work) |