Amoxicillin
Amoxicillin
Definition
A broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity. Amoxicillin binds to and inactivates penicillin-binding protein (PBP) 1A located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis.
Also known as AMOX, AMOXICILLIN, Amoxicillin Trihydrate, Amoxil, Polymox, Trimox, Utimox, Wymox — per NCIT
Also identified as
- ATC A02BD per NCIT
- ATC J01CA per NCIT
- NCIT NCIT:C237 per NCIT
Indications
| Disease | Relation | Source |
|---|---|---|
| Bacterial endocarditis | may prevent | MEDRT · Public domain (U.S. Government work) |
| Actinomycosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Chlamydia infectious disease | may treat | MEDRT · Public domain (U.S. Government work) |
| Duodenal ulcer | may treat | MEDRT · Public domain (U.S. Government work) |
| Helicobacter pylori infectious disease | may treat | MEDRT · Public domain (U.S. Government work) |
| Listeriosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Lyme disease | may treat | MEDRT · Public domain (U.S. Government work) |
| Otitis media | may treat | MEDRT · Public domain (U.S. Government work) |
| Sinusitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Skin disease caused by bacterial infection | may treat | MEDRT · Public domain (U.S. Government work) |
| Streptococcal infection | may treat | MEDRT · Public domain (U.S. Government work) |
| Urinary tract infection | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Alimentary part of gastrointestinal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Craniocervical region | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Ear | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Intestine | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Middle ear | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Small intestine | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Upper digestive tract | may treat a disease of this organ | DERIVED · CC BY 4.0 |
7 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.