Ofloxacin

Ofloxacin

Definition

A fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting in cell death in sensitive bacterial species. (NCI04)

Also known as 9-Fluoro-2,3-Dihydro-3-Methyl-10-(4-Methyl-1-Piperazinyl)-7-Oxo-7H-Pyrido(1,2,3-de)(1,4)benzoxazine-6-Carboxylic Acid, DL-, DL-8280, Floxin, HOE 280, Ocuflox, OFLOXACIN — per NCIT

Also identified as

Indications

Disease Relation Source
Bacterial conjunctivitis may treat MEDRT · Public domain (U.S. Government work)
Bronchitis may treat MEDRT · Public domain (U.S. Government work)
Chlamydia infectious disease may treat MEDRT · Public domain (U.S. Government work)
Corneal ulcer may treat MEDRT · Public domain (U.S. Government work)
Cystitis may treat MEDRT · Public domain (U.S. Government work)
Epididymitis may treat MEDRT · Public domain (U.S. Government work)
Escherichia coli infection may treat MEDRT · Public domain (U.S. Government work)
Gonorrhea may treat MEDRT · Public domain (U.S. Government work)
Haemophilus infectious disease may treat MEDRT · Public domain (U.S. Government work)
Helicobacter pylori infectious disease may treat MEDRT · Public domain (U.S. Government work)
Klebsiella infectious disease may treat MEDRT · Public domain (U.S. Government work)
Otitis externa may treat MEDRT · Public domain (U.S. Government work)
Prostatitis may treat MEDRT · Public domain (U.S. Government work)
Proteus infectious disease may treat MEDRT · Public domain (U.S. Government work)
Pulmonary tuberculosis may treat MEDRT · Public domain (U.S. Government work)
Salmonellosis may treat MEDRT · Public domain (U.S. Government work)
Skin disease caused by bacterial infection may treat MEDRT · Public domain (U.S. Government work)
Staphylococcal infection may treat MEDRT · Public domain (U.S. Government work)
Suppurative otitis media may treat MEDRT · Public domain (U.S. Government work)
Urinary tract infection may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Camera-type eye may treat a disease of this organ DERIVED · CC BY 4.0
Conjunctiva may treat a disease of this organ DERIVED · CC BY 4.0
Cornea may treat a disease of this organ DERIVED · CC BY 4.0
Craniocervical region may treat a disease of this organ DERIVED · CC BY 4.0
Ear may treat a disease of this organ DERIVED · CC BY 4.0
External ear may treat a disease of this organ DERIVED · CC BY 4.0
Genitourinary system may treat a disease of this organ DERIVED · CC BY 4.0
Lungs may treat a disease of this organ DERIVED · CC BY 4.0
Male reproductive system may treat a disease of this organ DERIVED · CC BY 4.0
Ocular adnexa may treat a disease of this organ DERIVED · CC BY 4.0
Prostate may treat a disease of this organ DERIVED · CC BY 4.0
Renal system may treat a disease of this organ DERIVED · CC BY 4.0
Reproductive system may treat a disease of this organ DERIVED · CC BY 4.0
Respiratory system may treat a disease of this organ DERIVED · CC BY 4.0
Urinary bladder may treat a disease of this organ DERIVED · CC BY 4.0

15 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.