Pimozide
Pimozide
Definition
A diphenylbutylpiperidine derivative and a dopamine antagonist with antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the central nervous system (CNS), thereby decreasing dopamine neurotransmission and reducing the occurrence of motor and vocal tics and delusions of parasitosis. In addition, this agent antagonizes alpha-adrenergic and 5-HT2 receptors.
Also known as 2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-, Opiran, Orap, PIMOZIDE — per NCIT
Also identified as
- ATC N05AG02 per RXNORM
- NCIT NCIT:C47672 per NCIT
- SCTID 108438008 per RXNORM
- SCTID 386848009 per RXNORM
- UNII 1HIZ4DL86F per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Huntington's disease | may treat | MEDRT · Public domain (U.S. Government work) |
| Tourette syndrome | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Central nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.