Pyrazinamide
ATC Code
J04AK01
Pyrazinamide
Definition
A synthetic pyrazinoic acid amide derivative with bactericidal property. Pyrazinamide is particularly active against slowly multiplying intracellular bacilli (unaffected by other drugs) by an unknown mechanism of action. Its bactericidal action is dependent upon the presence of bacterial pyrazinamidase, which removes the amide group to produce active pyrazinoic acid. Pyrazinamide is an important component of multidrug therapy for tuberculosis. (NCI04)
Also known as PYRAZINAMIDE — per NCIT
Also identified as
- ATC J04AK01 per RXNORM
- NCIT NCIT:C29395 per NCIT
- SCTID 13592004 per RXNORM
- SCTID 387076005 per RXNORM
- UNII 2KNI5N06TI per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Tuberculosis | may prevent | MEDRT · Public domain (U.S. Government work) |
| Tuberculosis | may treat | MEDRT · Public domain (U.S. Government work) |