Cromolyn
Cromolyn
Definition
A synthetic mast cell stabilizer with anti-inflammatory activity. Cromolyn probably interferes with the antigen-mediated calcium ion influx into mast cells. This prevents mast cell degranulation, resulting in mast cell stabilization and inhibition of the release of inflammatory mediators, such as histamine and leukotrienes, which are involved in type I allergic reactions. Cromolyn also prevents inflammatory mediator release from eosinophils.
Also known as 1,3-Bis(2-carboxychromon-5-yloxy)-2-hydroxypropane, 1,3-Di(2-carboxy-4-oxochromen-5-yloxy)propan-2-ol, 4H-1-Benzopyran-2-carboxylic acid, 5,5'-((2-hydroxy-1,3-propanediyl)bis(oxy))bis(4-oxo)-, Cromoglycate, CROMOLYN — per NCIT
Also identified as
- ATC A07EB01 per RXNORM
- ATC D11AH03 per RXNORM
- ATC R01AC01 per RXNORM
- ATC R03BC01 per RXNORM
- ATC S01GX01 per RXNORM
- NCIT NCIT:C61691 per NCIT
- SCTID 21701005 per RXNORM
- SCTID 372672009 per RXNORM
- UNII Y0TK0FS77W per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Asthma | may treat | MEDRT · Public domain (U.S. Government work) |
| Conjunctivitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Food allergy | may treat | MEDRT · Public domain (U.S. Government work) |
| Inflammatory bowel disease | may treat | MEDRT · Public domain (U.S. Government work) |
| Mastocytosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Perennial allergic rhinitis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Alimentary part of gastrointestinal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Camera-type eye | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Conjunctiva | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Craniocervical region | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Intestine | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Lungs | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nasal cavity | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Ocular adnexa | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Respiratory system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
9 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.