Rasburicase

Definition

A recombinant urate oxidase enzyme isolated from a genetically-modified strain of Saccharomyces cerevisiae. Urate oxidase catalyzes the oxidation of uric acid to the excretable metabolite allantoin, a molecule that is 5-10 times more water-soluble than uric acid. An enzyme that occurs endogenously in most mammals, urate oxidase is not found in humans. (NCI04)

Also known as Elitek, RASBURICASE, Recombinant Urate Oxidase, SR 29142, SR-29142, Urate Oxidase — per NCIT

Also identified as

• ATC V03AF07 per RXNORM
• NCIT NCIT:C2404 per NCIT
• SCTID 134670005 per RXNORM
• SCTID 395858003 per RXNORM
• SCTID 415249009 per RXNORM
• UNII 08GY9K1EUO per RXNORM

Indications