Tumor lysis syndrome
ICD-10 Code
E88.3
Tumor lysis syndrome
Definition
A condition of metabolic abnormalities that result from a spontaneous or therapy-related cytolysis of tumor cells. Tumor lysis syndrome typically occurs in aggressive, rapidly proliferating lymphoproliferative disorders. Burkitt lymphoma and T cell acute lymphoblastic leukemia are commonly associated with this syndrome. Metabolic abnormalities include hyperuricemia, lactic acidosis, hyperkalemia, hyperphosphatemia and hypocalcemia and may result in renal failure, multiple organ failure, and death.
Also known as tumor lysis syndrome — per MONDO
Also identified as
- ICD10CM E88.3 per MONDO
- MESH D015275 per MONDO
- NCIT C3425 per MONDO
- SCTID 277605001 per MONDO
- UMLS C0041364 per MONDO
Drugs indicated
| Drug | Relation | Source |
|---|---|---|
| Allopurinol | may prevent | MEDRT · Public domain (U.S. Government work) |
| Rasburicase | may treat | MEDRT · Public domain (U.S. Government work) |