Hyperparathyroidism

Hyperparathyroidism

Definition

Hyperfunction of the parathyroid glands resulting in the overproduction of parathyroid hormone. It may be primary or secondary; primary hyperparathyroidism is caused by parathyroid adenoma, parathyroid hyperplasia, parathyroid carcinoma, and multiple endocrine neoplasia. It is associated with hypercalcemia and hypophosphatemia. Signs and symptoms include weakness, fatigue, nausea, vomiting, constipation, depression, bone pain, osteoporosis, cystic bone lesions, and kidney stones. Secondary hyperparathyroidism is caused by the chronic stimulation of the parathyroid glands in patients with chronic renal failure, rickets, and malabsorption syndromes.

Also known as hyperparathyroidism — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Craniocervical region Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Craniocervical region Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Endocrine gland Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Neck Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Neck Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Parathyroid glands Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Parathyroid glands Disease Has Primary Anatomic Site NCIT · CC BY 4.0

Drugs indicated

Drug Relation Source
Paricalcitol may prevent MEDRT · Public domain (U.S. Government work)
Calcitriol may treat MEDRT · Public domain (U.S. Government work)
Doxercalciferol may treat MEDRT · Public domain (U.S. Government work)
Paricalcitol may treat MEDRT · Public domain (U.S. Government work)