Pancreatic endocrine carcinoma

Definition

An aggressive, high-grade and poorly differentiated carcinoma with neuroendocrine differentiation that arises from the pancreas. The mitotic count is more than 20 per 10 HPF. According to the size of the malignant cells, the prominence of the nucleoli, and the amount of cytoplasm, it is classified either as small or large cell neuroendocrine carcinoma.

Also known as carcinoma of endocrine pancreas, carcinoma, islet cell, malignant, endocrine pancreas carcinoma, high grade pancreatic neuroendocrine carcinoma, high-grade pancreatic neuroendocrine carcinoma, islet cell cancer, islet cell carcinoma, islet cell carcinoma (morphologic abnormality), malignant islet cell tumor, malignant islet cell tumour, malignant neoplasm of islets of Langerhans, malignant pancreatic endocrine tumor, malignant pancreatic endocrine tumour, pancreatic endocrine cancer, pancreatic endocrine carcinoma, pancreatic NEC, pancreatic NEC G3, Pancreatic Neuroendocrine cancer, pancreatic neuroendocrine carcinoma, poorly differentiated pancreatic endocrine carcinoma, poorly-differentiated NEN of pancreas, poorly-differentiated neuroendocrine neoplasm of pancreas, poorly-differentiated pancreatic NEN, poorly-differentiated pancreatic neuroendocrine neoplasm — per MONDO

Also identified as

• DOID 1798 per MONDO
• ICD10CM C25.4 per MONDO
• ICD9 157.4 per MONDO
• MESH D018273 per MONDO
• NCIT C3770 per MONDO
• Orphanet 506098 per MONDO
• SCTID 254612002 per MONDO
• UMLS C1328479 per MONDO

Affected Organs

Drugs indicated