Azithromycin

ATC Code J01FA10

Azithromycin

Definition

An azalide, derived from erythromycin, and a member of a subclass of macrolide antibiotics with bacteriocidal and bacteriostatic activities. Azithromycin reversibly binds to the 50S ribosomal subunit of the 70S ribosome of sensitive microorganisms, thereby inhibiting the translocation step of protein synthesis, wherein a newly synthesized peptidyl tRNA molecule moves from the acceptor site on the ribosome to the peptidyl (donor) site, and consequently inhibiting RNA-dependent protein synthesis leading to cell growth inhibition and cell death.

Also known as (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[(3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentade, AzaSite, Azithromycin, AZITHROMYCIN, UNSPECIFIED FORM, CP 62993, N-methyl-11-aza-10-deoxy-10-dihydroerythromycin A, XZ-450, Zithromax — per NCIT

Also identified as

Indications

Disease Relation Source
Bacterial endocarditis may prevent MEDRT · Public domain (U.S. Government work)
Bacterial infectious disease may prevent MEDRT · Public domain (U.S. Government work)
Protozoa infectious disease may prevent MEDRT · Public domain (U.S. Government work)
Bacterial infectious disease may treat MEDRT · Public domain (U.S. Government work)
Chlamydia infectious disease may treat MEDRT · Public domain (U.S. Government work)
Haemophilus infectious disease may treat MEDRT · Public domain (U.S. Government work)
Mycoplasma pneumoniae pneumonia may treat MEDRT · Public domain (U.S. Government work)
Otitis media may treat MEDRT · Public domain (U.S. Government work)
Protozoa infectious disease may treat MEDRT · Public domain (U.S. Government work)
Skin disorder caused by infection may treat MEDRT · Public domain (U.S. Government work)
Staphylococcal infection may treat MEDRT · Public domain (U.S. Government work)
Streptococcal infection may treat MEDRT · Public domain (U.S. Government work)
Tonsillitis may treat MEDRT · Public domain (U.S. Government work)
Urethritis may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Craniocervical region may treat a disease of this organ DERIVED · CC BY 4.0
Ear may treat a disease of this organ DERIVED · CC BY 4.0
Genitourinary system may treat a disease of this organ DERIVED · CC BY 4.0
Lungs may treat a disease of this organ DERIVED · CC BY 4.0
Middle ear may treat a disease of this organ DERIVED · CC BY 4.0
Renal system may treat a disease of this organ DERIVED · CC BY 4.0
Respiratory system may treat a disease of this organ DERIVED · CC BY 4.0
Tonsils may treat a disease of this organ DERIVED · CC BY 4.0
Urethra may treat a disease of this organ DERIVED · CC BY 4.0

9 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.