Clarithromycin

ATC Code J01FA09

Clarithromycin

Definition

A semisynthetic 14-membered ring macrolide antibiotic. Clarithromycin binds to the 50S ribosomal subunit and inhibits RNA-dependent protein synthesis in susceptible organisms. Clarithromycin has been shown to eradicate gastric MALT (mucosa-associated lymphoid tissue) lymphomas, presumably due to the eradication of tumorigenic Helicobacter pylori infection. This agent also acts as a biological response modulator, possibly inhibiting angiogenesis and tumor growth through alterations in growth factor expression. (NCI04)

Also known as 6-O-Methylerythromycin, Abbott-56268, Biaxin, CLARITHROMYCIN — per NCIT

Also identified as

Indications

Disease Relation Source
Bacterial endocarditis may prevent MEDRT · Public domain (U.S. Government work)
Bronchitis may treat MEDRT · Public domain (U.S. Government work)
Chlamydia infectious disease may treat MEDRT · Public domain (U.S. Government work)
Duodenal ulcer may treat MEDRT · Public domain (U.S. Government work)
Haemophilus infectious disease may treat MEDRT · Public domain (U.S. Government work)
Helicobacter pylori infectious disease may treat MEDRT · Public domain (U.S. Government work)
Mycoplasma pneumoniae pneumonia may treat MEDRT · Public domain (U.S. Government work)
Otitis media may treat MEDRT · Public domain (U.S. Government work)
Sinusitis may treat MEDRT · Public domain (U.S. Government work)
Skin disorder caused by infection may treat MEDRT · Public domain (U.S. Government work)
Staphylococcal infection may treat MEDRT · Public domain (U.S. Government work)
Streptococcal infection may treat MEDRT · Public domain (U.S. Government work)
Tonsillitis may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Alimentary part of gastrointestinal system may treat a disease of this organ DERIVED · CC BY 4.0
Craniocervical region may treat a disease of this organ DERIVED · CC BY 4.0
Ear may treat a disease of this organ DERIVED · CC BY 4.0
Intestine may treat a disease of this organ DERIVED · CC BY 4.0
Lungs may treat a disease of this organ DERIVED · CC BY 4.0
Middle ear may treat a disease of this organ DERIVED · CC BY 4.0
Respiratory system may treat a disease of this organ DERIVED · CC BY 4.0
Small intestine may treat a disease of this organ DERIVED · CC BY 4.0
Tonsils may treat a disease of this organ DERIVED · CC BY 4.0
Upper digestive tract may treat a disease of this organ DERIVED · CC BY 4.0

10 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.