Interferon Gamma-1b

Interferon Gamma-1b

Definition

A recombinant form of the endogenous cytokine human interferon (IFN) gamma-1b, with immunomodulating activity. Upon administration, IFN gamma-1b targets, binds to, and activates the cell-surface IFN-gamma receptor, stimulating antibody dependent cellular cytotoxicity (ADCC), activating natural killer (NK) cells, and enhancing the oxidative metabolism of macrophages. IFN-gamma plays important roles in the innate and adaptive immune responses.

Also known as Actimmune, gamma Interferon 1B, IFN-g-1b, IFN-gamma 1b, IFNg-1b, INTERFERON GAMMA-1B, Interferon gamma-1b, Recombinant, N(Sup 2)-L-Methionyl-1-139-Interferon G, N(sup 2)-L-Methionyl-1-139-interferon gamma (Human Lymphocyte Protein Moiety Reduced), Recombinant Interferon Gamma-1b — per NCIT

Also identified as

Indications

Disease Relation Source
Bacterial infectious disease may treat MEDRT · Public domain (U.S. Government work)
Brain cancer may treat MEDRT · Public domain (U.S. Government work)
Chronic hepatitis C virus infection may treat MEDRT · Public domain (U.S. Government work)
Colorectal neoplasm may treat MEDRT · Public domain (U.S. Government work)
Common wart may treat MEDRT · Public domain (U.S. Government work)
Cryoglobulinemia may treat MEDRT · Public domain (U.S. Government work)
Essential thrombocythemia may treat MEDRT · Public domain (U.S. Government work)
Hairy cell leukemia may treat MEDRT · Public domain (U.S. Government work)
Hemangioma may treat MEDRT · Public domain (U.S. Government work)
Hepatitis D virus infection may treat MEDRT · Public domain (U.S. Government work)
Hepatocellular carcinoma may treat MEDRT · Public domain (U.S. Government work)
Hypereosinophilic syndrome may treat MEDRT · Public domain (U.S. Government work)
Ileal neoplasm may treat MEDRT · Public domain (U.S. Government work)
Kaposi's sarcoma may treat MEDRT · Public domain (U.S. Government work)
Macular degeneration may treat MEDRT · Public domain (U.S. Government work)
Melanoma may treat MEDRT · Public domain (U.S. Government work)
Multiple myeloma may treat MEDRT · Public domain (U.S. Government work)
Mycosis fungoides may treat MEDRT · Public domain (U.S. Government work)
Osteopetrosis may treat MEDRT · Public domain (U.S. Government work)
Renal cell carcinoma may treat MEDRT · Public domain (U.S. Government work)
Sezary syndrome may treat MEDRT · Public domain (U.S. Government work)
Skin neoplasm may treat MEDRT · Public domain (U.S. Government work)
Thrombocytopenia may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Alimentary part of gastrointestinal system may treat a disease of this organ DERIVED · CC BY 4.0
Blood vessel may treat a disease of this organ DERIVED · CC BY 4.0
Bone element may treat a disease of this organ DERIVED · CC BY 4.0
Bone marrow may treat a disease of this organ DERIVED · CC BY 4.0
Camera-type eye may treat a disease of this organ DERIVED · CC BY 4.0
Liver may treat a disease of this organ DERIVED · CC BY 4.0
Lymphoid system may treat a disease of this organ DERIVED · CC BY 4.0
Musculoskeletal system may treat a disease of this organ DERIVED · CC BY 4.0
Retina may treat a disease of this organ DERIVED · CC BY 4.0
Skin of body may treat a disease of this organ DERIVED · CC BY 4.0

10 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.