Methylprednisolone

Methylprednisolone

Definition

A synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone binds to and activates specific nuclear receptors, resulting in altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations.

Also known as (6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione, 6Alpha-Methylprednisolone, Adlone, Caberdelta M, DepMedalone, Depo Moderin, Depo-Nisolone, Duralone, Emmetipi, Esametone, Firmacort, Medlone 21, Medrate, Medrol, Medrol Veriderm, Medrone, Mega-Star, Meprolone, METHYLPREDNISOLONE, Methylprednisolonum, Metilbetasone Solubile, Metrocort, Metypresol, Metysolon, Predni-M-Tablinen, Prednilen, Radilem, Sieropresol, Solpredone, Summicort, Urbason, Veriderm Medrol, Wyacort — per NCIT

Also identified as

Indications

Disease Relation Source
Graft versus host disease may prevent MEDRT · Public domain (U.S. Government work)
Rheumatoid arthritis may prevent MEDRT · Public domain (U.S. Government work)
Adrenocortical insufficiency may treat MEDRT · Public domain (U.S. Government work)
Adult acute respiratory distress syndrome may treat MEDRT · Public domain (U.S. Government work)
Ankylosing spondylitis may treat MEDRT · Public domain (U.S. Government work)
Asthma may treat MEDRT · Public domain (U.S. Government work)
Atopic eczema may treat MEDRT · Public domain (U.S. Government work)
Brain cancer may treat MEDRT · Public domain (U.S. Government work)
Chronic beryllium disease may treat MEDRT · Public domain (U.S. Government work)
Dermatitis herpetiformis may treat MEDRT · Public domain (U.S. Government work)
Erythema multiforme may treat MEDRT · Public domain (U.S. Government work)
Graft versus host disease may treat MEDRT · Public domain (U.S. Government work)
Hematologic disorder may treat MEDRT · Public domain (U.S. Government work)
Hypercalcemia disease may treat MEDRT · Public domain (U.S. Government work)
Leukemia may treat MEDRT · Public domain (U.S. Government work)
Multiple sclerosis may treat MEDRT · Public domain (U.S. Government work)
Mycosis fungoides may treat MEDRT · Public domain (U.S. Government work)
Nephrotic syndrome may treat MEDRT · Public domain (U.S. Government work)
Pemphigus may treat MEDRT · Public domain (U.S. Government work)
Pulmonary tuberculosis may treat MEDRT · Public domain (U.S. Government work)
Rheumatic disorder may treat MEDRT · Public domain (U.S. Government work)
Sarcoidosis may treat MEDRT · Public domain (U.S. Government work)
Serum sickness may treat MEDRT · Public domain (U.S. Government work)
Synovitis may treat MEDRT · Public domain (U.S. Government work)
Systemic lupus erythematosus may treat MEDRT · Public domain (U.S. Government work)
Thyroiditis may treat MEDRT · Public domain (U.S. Government work)
Ulcerative colitis may treat MEDRT · Public domain (U.S. Government work)
Uveitis may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Adrenal glands may treat a disease of this organ DERIVED · CC BY 4.0
Adult mammalian kidney may treat a disease of this organ DERIVED · CC BY 4.0
Alimentary part of gastrointestinal system may treat a disease of this organ DERIVED · CC BY 4.0
Bone element may treat a disease of this organ DERIVED · CC BY 4.0
Bone marrow may treat a disease of this organ DERIVED · CC BY 4.0
Camera-type eye may treat a disease of this organ DERIVED · CC BY 4.0
Central nervous system may treat a disease of this organ DERIVED · CC BY 4.0
Craniocervical region may treat a disease of this organ DERIVED · CC BY 4.0
Genitourinary system may treat a disease of this organ DERIVED · CC BY 4.0
Intestine may treat a disease of this organ DERIVED · CC BY 4.0
Lungs may treat a disease of this organ DERIVED · CC BY 4.0
Lymphoid system may treat a disease of this organ DERIVED · CC BY 4.0
Musculoskeletal system may treat a disease of this organ DERIVED · CC BY 4.0
Neck may treat a disease of this organ DERIVED · CC BY 4.0
Nervous system may treat a disease of this organ DERIVED · CC BY 4.0
Renal system may treat a disease of this organ DERIVED · CC BY 4.0
Respiratory system may treat a disease of this organ DERIVED · CC BY 4.0
Skeletal joint may treat a disease of this organ DERIVED · CC BY 4.0
Skin of body may treat a disease of this organ DERIVED · CC BY 4.0
Thyroid gland may treat a disease of this organ DERIVED · CC BY 4.0
Uvea may treat a disease of this organ DERIVED · CC BY 4.0

21 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.