Serum sickness

Definition

Delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest pain, and dyspnea. Certain drugs (e.g., antibiotics, anticancer agents, and anti-inflammatory medications) and infectious disorders (e.g., hepatitis B) may also cause serum sickness-like reaction.

Also known as serum sickness, transfusion reaction due to serum protein reaction — per MONDO

Also identified as

• MESH D012713 per MONDO
• NCIT C79718 per MONDO
• SCTID 72284000 per MONDO
• UMLS C0036830 per MONDO

Drugs indicated