Prednisolone
Prednisolone
Definition
A synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. (NCI04)
Also known as .delta.1-Hydrocortisone, (11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione, 1,2-Dehydrohydrocortisone, Adnisolone, Aprednislon, Capsoid, Cortalone, Cortisolone, Dacortin H, Decaprednil, Decortin H, Delta- Cortef, Delta-Cortef, Delta-Diona, Delta-F, Delta-Phoricol, Delta(1)Hydrocortisone, Delta1-dehydro-hydrocortisone, Deltacortril, Deltahydrocortisone, Deltasolone, Deltidrosol, Dhasolone, Di-Adreson-F, Dontisolon D, Estilsona, Fisopred, Frisolona, Gupisone, Hostacortin H, Hydeltra, Hydeltrasol, Klismacort, Kuhlprednon, Lenisolone, Lepi-Cortinolo, Linola-H N, Linola-H-Fett N, Longiprednil, Metacortandralone, Meti Derm, Meticortelone, Opredsone, Panafcortelone, Precortisyl, Pred-Clysma, Predeltilone, Predni-Coelin, Predni-Helvacort, Prednicortelone, PREDNISOLONE, Prednisolonum, Prelone, Prenilone, Sterane — per NCIT
Also identified as
- ATC A01AC04 per RXNORM
- ATC A07EA01 per RXNORM
- ATC C05AA04 per RXNORM
- ATC D07AA03 per RXNORM
- ATC D07XA02 per RXNORM
- ATC H02AB06 per RXNORM
- ATC R01AD02 per RXNORM
- ATC S01BA04 per RXNORM
- ATC S01CB02 per RXNORM
- ATC S02BA03 per RXNORM
- ATC S03BA02 per RXNORM
- NCIT NCIT:C769 per NCIT
- SCTID 116601002 per RXNORM
- SCTID 52388000 per RXNORM
- UNII 9PHQ9Y1OLM per RXNORM
Indications
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Adrenal glands | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Adult mammalian kidney | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Alimentary part of gastrointestinal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Bone element | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Bone marrow | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Camera-type eye | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Central nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Conjunctiva | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Craniocervical region | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Genitourinary system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Intestine | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Lungs | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Lymphoid system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Musculoskeletal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Neck | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Ocular adnexa | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Renal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Respiratory system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Skeletal joint | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Skin of body | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Thyroid gland | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Uvea | may treat a disease of this organ | DERIVED · CC BY 4.0 |
23 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.