Sulfamethoxazole
Sulfamethoxazole
Definition
A sulfonamide bacteriostatic antibiotic that is most commonly used in combination with trimethoprim as the drug Bactrim. Sulfamethoxazole competitively inhibits dihydropteroate synthase preventing the formation of dihydropteroic acid, a precursor of folic acid which is required for bacterial growth.
Also known as Benzenesulfonamide, 4-amino-N-(5-methyl-3-isoxazolyl)-, Gamazole, Metoxal, Radonil, SULFAMETHOXAZOLE, Sulfanilamide, N'-(5-methyl-3-isoxazolyl)-, Sulfisomezole — per NCIT
Also identified as
- ATC J01EC01 per RXNORM
- NCIT NCIT:C47737 per NCIT
- SCTID 363528007 per RXNORM
- SCTID 70047000 per RXNORM
- UNII JE42381TNV per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Chlamydiaceae infections | may treat | MEDRT · Public domain (U.S. Government work) |
| Chronic bronchitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Nocardiosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Otitis media | may treat | MEDRT · Public domain (U.S. Government work) |
| Pneumocystosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Toxoplasmosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Urinary tract infection | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Craniocervical region | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Ear | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Lungs | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Middle ear | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Respiratory system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
5 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.