Pneumocystosis
Pneumocystosis
Definition
Human pneumocystosis is caused by an infectious agent, which (after recent nomenclature and taxonomy revisions) is now classed as the fungus Pneumocystis jiroveci. The prevalence is unknown. Pneumocystis jiroveci is an opportunistic infectious agent, developing in immunosuppressed patients. It is an air-borne infection, localized to the lungs. However, extrapulmonary involvement is seen in AIDS patients. The disease manifests progressively with coughing, respiratory problems (dyspnea) and fever, followed by acute respiratory insufficiency and death within a few weeks in untreated cases. The most reliable diagnostic method is bronchoalveolar lavage. The treatment of choice is cotrimoxazole.
Also known as PCP, PJP, Pneumocystis, Pneumocystis carinii pneumonia, Pneumocystis jirovecii pneumonia, Pneumocystis Pneumonia, pneumocystosis — per MONDO
Also identified as
- DOID 11339 per MONDO
- ICD10CM B59 per MONDO
- ICD9 136.3 per MONDO
- MESH D011020 per MONDO
- NCIT C3334 per MONDO
- Orphanet 723 per MONDO
- SCTID 415125002 per MONDO
- UMLS C1535939 per MONDO
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Lungs | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Lungs | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Respiratory system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Respiratory system | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
Drugs indicated
| Drug | Relation | Source |
|---|---|---|
| Atovaquone | may prevent | MEDRT · Public domain (U.S. Government work) |
| Pentamidine | may prevent | MEDRT · Public domain (U.S. Government work) |
| Atovaquone | may treat | MEDRT · Public domain (U.S. Government work) |
| Clindamycin | may treat | MEDRT · Public domain (U.S. Government work) |
| Pentamidine | may treat | MEDRT · Public domain (U.S. Government work) |
| Sulfamethoxazole | may treat | MEDRT · Public domain (U.S. Government work) |
| Trimethoprim | may treat | MEDRT · Public domain (U.S. Government work) |