Cefpodoxime
Cefpodoxime
Definition
A third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefpodoxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefpodoxime inhibits bacterial septum and cell wall synthesis formation.
Also known as CEFPODOXIME — per NCIT
Also identified as
- ATC J01DD13 per RXNORM
- NCIT NCIT:C65305 per NCIT
- SCTID 387534007 per RXNORM
- SCTID 96049003 per RXNORM
- UNII 7R4F94TVGY per RXNORM
Indications
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Chordate pharynx | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Craniocervical region | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Ear | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Genitourinary system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Lungs | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Middle ear | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Neck | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Renal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Respiratory system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Tonsils | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Urinary bladder | may treat a disease of this organ | DERIVED · CC BY 4.0 |
11 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.