Interferon Beta-1B

ATC Code L03AB08

Interferon Beta-1B

Definition

A recombinant and modified form of the endogenous cytokine human interferon (IFN) beta-1b, with antiproliferative, antiviral and immunomodulating activities. Upon administration, interferon beta-1b targets and binds to specific type I IFN receptors, which eventually results in the transcription and translation of genes containing an interferon-specific response element and leads to the production of various anti-viral proteins and modulates the production of various immune-modulating proteins. This reduces the production of certain pro-inflammatory cytokines while upregulating the anti-inflammatory cytokine interleukin 10 (IL-10), upregulates the expression of major histocompatibility (MHC) I proteins which allows for increased presentation of peptides derived from viral antigens, and activates CD8+ T cells as well as other immune cells. Endogenous IFN-beta-1b is produced following viral infection and it plays a key role in innate immune response against viral pathogens.

Also known as Beta-ser-interferon, Betaferon, Betaseron, INTERFERON BETA-1B, Recombinant interferon beta-1b — per NCIT

Also identified as

Indications

Disease Relation Source
Brain cancer may treat MEDRT · Public domain (U.S. Government work)
Chronic hepatitis C virus infection may treat MEDRT · Public domain (U.S. Government work)
Colorectal neoplasm may treat MEDRT · Public domain (U.S. Government work)
Common wart may treat MEDRT · Public domain (U.S. Government work)
Cryoglobulinemia may treat MEDRT · Public domain (U.S. Government work)
Essential thrombocythemia may treat MEDRT · Public domain (U.S. Government work)
Hairy cell leukemia may treat MEDRT · Public domain (U.S. Government work)
Hemangioma may treat MEDRT · Public domain (U.S. Government work)
Hepatitis D virus infection may treat MEDRT · Public domain (U.S. Government work)
Hepatocellular carcinoma may treat MEDRT · Public domain (U.S. Government work)
Hypereosinophilic syndrome may treat MEDRT · Public domain (U.S. Government work)
Ileal neoplasm may treat MEDRT · Public domain (U.S. Government work)
Kaposi's sarcoma may treat MEDRT · Public domain (U.S. Government work)
Macular degeneration may treat MEDRT · Public domain (U.S. Government work)
Melanoma may treat MEDRT · Public domain (U.S. Government work)
Multiple myeloma may treat MEDRT · Public domain (U.S. Government work)
Multiple sclerosis may treat MEDRT · Public domain (U.S. Government work)
Mycosis fungoides may treat MEDRT · Public domain (U.S. Government work)
Renal cell carcinoma may treat MEDRT · Public domain (U.S. Government work)
Sezary syndrome may treat MEDRT · Public domain (U.S. Government work)
Skin neoplasm may treat MEDRT · Public domain (U.S. Government work)
Thrombocytopenia may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Alimentary part of gastrointestinal system may treat a disease of this organ DERIVED · CC BY 4.0
Blood vessel may treat a disease of this organ DERIVED · CC BY 4.0
Bone marrow may treat a disease of this organ DERIVED · CC BY 4.0
Camera-type eye may treat a disease of this organ DERIVED · CC BY 4.0
Central nervous system may treat a disease of this organ DERIVED · CC BY 4.0
Liver may treat a disease of this organ DERIVED · CC BY 4.0
Lymphoid system may treat a disease of this organ DERIVED · CC BY 4.0
Nervous system may treat a disease of this organ DERIVED · CC BY 4.0
Retina may treat a disease of this organ DERIVED · CC BY 4.0
Skin of body may treat a disease of this organ DERIVED · CC BY 4.0

10 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.