B-cell chronic lymphocytic leukemia

Definition

B-cell chronic lymphocytic leukemia (B-CLL) is a type of B-cell non-Hodgkin lymphoma, and the most common form of leukemia in Western countries, affecting elderly adults (mean age of 67 and 72 years) with a slight male predominance (1.7:1), and characterized by a highly variable clinical presentation that can include asymptomatic disease or non-specific B-symptoms such as unintentional weight loss, severe fatigue, fever (without evidence of infection), and night sweats as well as cervical lymphadenopathy, splenomegaly and frequent infections. Some patients can also develop autoimmune complications such as autoimmune hemolytic anemia or immune thrombocytopenia. The clinical course is extremely heterogeneous with survival ranging from a few months to several decades.

Also known as B cell chronic lymphocytic leukaemia, B cell chronic lymphocytic leukemia, B cell CLL, B cell lymphocytic leukaemia, B cell lymphocytic leukemia, B-cell chronic lymphocytic leukemia, B-cell chronic lymphogenous leukaemia, B-cell chronic lymphogenous leukemia, B-cell chronic lymphoid leukaemia, B-cell chronic lymphoid leukemia, B-cell CLL, B-cell lymphocytic leukaemia, B-cell lymphocytic leukemia, B-CLL, BCLL, chronic B-cell lymphocytic leukaemia, chronic B-cell lymphocytic leukemia, chronic lymphatic leukemia, chronic lymphocytic leukaemia (CLL), Chronic Lymphocytic Leukemia, chronic lymphocytic leukemia (CLL), chronic lymphogenous leukaemia, chronic lymphogenous leukemia, CLL, hematopoeitic - chronic lymphocytic leukaemia (CLL), hematopoeitic - chronic lymphocytic leukemia (CLL), lymphoplasmacytic leukemia — per MONDO

Also identified as

• DOID 1040 per MONDO
• ICD10CM C91.1 per MONDO
• ICD9 204.1 per MONDO
• MESH D015451 per MONDO
• NCIT C3163 per MONDO
• OMIM 151400 per MONDO
• Orphanet 67038 per MONDO
• UMLS C0023434 per MONDO

Affected Organs

Drugs indicated