Small cell lung carcinoma

Small cell lung carcinoma

Definition

Small cell lung cancer (SCLC) is a highly aggressive malignant neoplasm, accounting for 10-15% of lung cancer cases, characterized byrapid growth, and early metastasis. SCLC usually manifests as a large hilar mass with bulky mediastinal lymphadenopathy presenting clinically with chest pain, persistent cough, dyspnea, wheezing, hoarseness, hemoptysis, loss of appetite, weight loss, and neurological and endocrine paraneoplastic syndromes. SCLC is primarily reported in elderly people with a history of long-term tobacco exposure.

Also known as lung oat cell carcinoma, lung small cell carcinoma, lung small cell neuroendocrine carcinoma, oat cell carcinoma of lung, oat cell carcinoma of the lung, oat cell lung carcinoma, small cell cancer of the lung, somatic, small cell carcinoma of lung, small cell carcinoma of the lung, Small cell lung cancer, small cell neuroendocrine carcinoma of lung, small cell neuroendocrine carcinoma of the lung, small-cell cancer of lung — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Bronchi Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Endocrine gland Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Endocrine gland Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Lungs Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Lungs Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Respiratory system Disease Has Associated Anatomic Site NCIT · CC BY 4.0

Drugs indicated

Drug Relation Source
Atezolizumab may treat MEDRT · Public domain (U.S. Government work)
Lurbinectedin may treat MEDRT · Public domain (U.S. Government work)
Nivolumab may treat MEDRT · Public domain (U.S. Government work)
Topotecan may treat MEDRT · Public domain (U.S. Government work)
Zenocutuzumab may treat MEDRT · Public domain (U.S. Government work)