Squamous cell carcinoma

Definition

A carcinoma arising from squamous epithelial cells. Morphologically, it is characterized by the proliferation of atypical, often pleomorphic squamous cells. Squamous cell carcinomas are graded by the degree of cellular differentiation as well, moderately, or poorly differentiated. Well differentiated carcinomas are usually associated with keratin production and the presence of intercellular bridges between adjacent cells. Representative examples are lung squamous cell carcinoma, skin squamous cell carcinoma, and cervical squamous cell carcinoma.

Also known as carcinoma, squamous cell, malignant, epidermoid carcinoma, epidermoid cell cancer, malignant epidermoid cell neoplasm, malignant epidermoid cell tumor, malignant epidermoid cell tumour, malignant squamous cell neoplasm, malignant squamous cell tumor, malignant squamous cell tumour, squamous carcinoma, squamous cell cancer, squamous cell carcinoma, squamous cell carcinoma (morphologic abnormality), squamous cell carcinoma NOS (morphologic abnormality), squamous cell epithelioma — per MONDO

Also identified as

• DOID 1749 per MONDO
• MESH D002294 per MONDO
• NCIT C2929 per MONDO
• SCTID 402815007 per MONDO
• UMLS C0007137 per MONDO

Drugs indicated