Clostridium difficile colitis
Clostridium difficile colitis
Definition
A bacterial infection of the colon secondary to infection with Clostridium difficile bacteria. This infection generally results from the loss of normal gut flora secondary to recent antibiotic use, and manifests as copious watery stools, with associated abdominal pain and myalgia. C. difficile is the most common cause of pseudomembranous colitis, and can progress to toxic megacolon if left untreated.
Also known as C. diff colitis, C. diff infection, Clostridioides difficile caused colitis (disease), Clostridioides difficile colitis (disease), Clostridium difficile infection, pseudomembranous colitis — per MONDO
Also identified as
- DOID 0060185 per MONDO
- MESH D004761 per MONDO
- NCIT C35286 per MONDO
- SCTID 423590009 per MONDO
- UMLS C0238106 per MONDO
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Alimentary part of gastrointestinal system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Alimentary part of gastrointestinal system | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Colon | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Colon | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Intestine | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Intestine | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Large intestine | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
Drugs indicated
| Drug | Relation | Source |
|---|---|---|
| Bacitracin | may treat | MEDRT · Public domain (U.S. Government work) |
| Cholestyramine | may treat | MEDRT · Public domain (U.S. Government work) |
| Colesevelam | may treat | MEDRT · Public domain (U.S. Government work) |
| Colestipol | may treat | MEDRT · Public domain (U.S. Government work) |
| Fidaxomicin | may treat | MEDRT · Public domain (U.S. Government work) |
| Metronidazole | may treat | MEDRT · Public domain (U.S. Government work) |
| Vancomycin | may treat | MEDRT · Public domain (U.S. Government work) |