Parkinson's disease

ICD-10 Code G20
Category Neurological

Parkinson's disease

Definition

A progressive degenerative disorder of the central nervous system characterized by loss of dopamine producing neurons in the substantia nigra and the presence of Lewy bodies in the substantia nigra and locus coeruleus. Signs and symptoms include tremor which is most pronounced during rest, muscle rigidity, slowing of the voluntary movements, a tendency to fall back, and a mask-like facial expression.

Also known as paralysis agitans, Parkinson disease, Parkinson's disease, PD — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Central nervous system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Central nervous system Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Nervous system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Nervous system Disease Has Primary Anatomic Site NCIT · CC BY 4.0

Drugs indicated

Drug Relation Source
Amantadine may treat MEDRT · Public domain (U.S. Government work)
Bromocriptine may treat MEDRT · Public domain (U.S. Government work)
Cabergoline may treat MEDRT · Public domain (U.S. Government work)
Carbidopa may treat MEDRT · Public domain (U.S. Government work)
Entacapone may treat MEDRT · Public domain (U.S. Government work)
Levodopa may treat MEDRT · Public domain (U.S. Government work)
Levodopa + Carbidopa may treat MEDRT · Public domain (U.S. Government work)
Rotigotine may treat MEDRT · Public domain (U.S. Government work)
Selegiline may treat MEDRT · Public domain (U.S. Government work)
Tolcapone may treat MEDRT · Public domain (U.S. Government work)